Application of pharmaceutical packaging materials

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Application of pharmaceutical packaging materials and containers in China

with the rapid development of social economy, the pharmaceutical packaging industry is becoming more and more popular. China is constantly introducing and updating pharmaceutical packaging machinery and materials, and the pharmaceutical packaging industry will present a new situation. The diversification of drug types also brings diversification to the forms of pharmaceutical packaging, and accelerates the development of pharmaceutical packaging industry. Pharmaceutical packaging is the packaging of special commodities. Since the processing and molding of drugs, it plays an important role in protecting the safety and effectiveness of drugs, facilitating transportation, storage, sales and use, and can be called the "second life" of drugs. Pharmaceutical glass packaging

glass containers are commonly used for the packaging of injections (including powder injection, freeze-dried powder injection and small volume injection), large volume infusion and other dosage forms. Among them, the use of molded injection bottles accounts for 70% of the total packaging of antibiotic powder injections, and controlled injection bottles have become the first choice for biological agents because of their light weight, high transparency and small capacity. During the use of medical glass packaging, attention should be paid to the problems that the release of alkaline ions will lead to changes in the pH value of the drug solution, protein and polypeptide drugs are adsorbed by glass, drugs are decomposed by light, and the clarity of drugs is changed by glass disintegration. In addition, when the glass container is poorly prepared, problems such as fusion sealing pinholes, crooked bottle mouth, poor sealing will also occur

in recent years, China Pharmaceutical glass branch has developed silicified coated bottles, which are suitable for drugs with poor packaging stability, such as suspensions. Due to the specificity and scarcity of its technology, the price of coated glass bottles is high at present

pharmaceutical rubber packaging materials

rubber used in drug packaging mainly appears in the form of plugs and gaskets of containers, mainly including natural rubber and butyl rubber. Due to its poor sealing performance, natural rubber plugs often need sealing wax to supplement, and because the vulcanizate of natural rubber plugs contains more double bonds and its chemical properties are unstable, it has been listed in the list of elimination. Butyl rubber stopper is increasingly used in the packaging of antibiotic powder injection because of its excellent sealing performance. At present, the main problem is that the interaction between the drug and the rubber plug makes the clarity of the drug unstable. Therefore, drug manufacturers have conducted a large number of tests on the compatibility between rubber plugs and drugs, and tried to screen out special rubber plugs suitable for the drug through tests. For the stability of drugs, coated rubber plugs came into being, but they have not been popularized because of their high price

pharmaceutical metal packaging materials

pharmaceutical metal packaging materials mainly refer to aluminum caps, pastes and aerosol bottles used for powder injection packaging, as well as pharmaceutical aluminum foil packaged with aluminum plastic blisters. There are several kinds of aluminum caps for powder injection: E-type non flowering aluminum cap (often used with natural rubber plug with wax sealing process), the use of C-type three electronic universal experimental machine and the working principle of deformation measurement. Do you know? Now let's take a look with Xiaobian 1. Connect the bridge flowering aluminum cover and aluminum plastic composite cover. Aluminum strips for processing are usually semi-rigid pure aluminum or h14-h16 alloy aluminum strips. Aluminum plastic composite cover has been more and more accepted by the market because of its convenient opening and safe and sanitary use

aluminum aluminum packaging developed in recent years is a new packaging material developed by European pharmaceutical packaging material Lawson mardon. It has a strong barrier, so that the shelf life of drugs is extended. Therefore, aluminum aluminum packaging materials are the best packaging materials and packaging forms for drugs with poor chemical stability

pharmaceutical composite packaging materials

mainly include oral solid pharmaceutical plastic bottles, liquid pharmaceutical plastic bottles and plastic bottles for eye drops. These plastic bottles are mostly made of high-density polyethylene (low-density polyethylene for eye drop packaging bottles) or polypropylene and polyester materials. Polyester bottles have become a bright spot in the pharmaceutical packaging market because of their light weight, high transparency and good barrier

medicinal polyvinyl chloride (PVC) is the underlying material of aluminum-plastic blister packaging. In order to improve the barrier property of PVC hard sheet, pvc/pvdc composite hard sheet can be selected, or cold aluminum "lunch box" packaging can be selected, and desiccant and aluminum plastic composite bag packaging can be added. The latest materials for moisture-proof packaging and environmental protection packaging should be the COC composite materials produced by European propack company. COC has considerable advantages in cost performance

there are various forms of pharmaceutical composite films and bags, including paper/plastic, plastic/aluminized plastic, paper/aluminum foil/plastic and plastic/aluminum foil/plastic, and their barrier properties increase in turn. Among them, the materials of plastics can be divided into PE, CPP, BOPR, BOPET, BOPA, etc. the composite methods include dry composite method, wet composite method (both referred to as laminated composite), extrusion composite, coextrusion composite and other methods. The most commonly used composite process is dry composite process. It is not only applicable to the compounding between plastic films, but also applicable to the compounding between plastic films and aluminum foil, aluminum plating film. Drug manufacturers can choose appropriate pharmaceutical packaging according to the barrier performance requirements of drugs on packaging materials and the form of drug packaging to reduce energy consumption, and comprehensively consider other factors such as transparency, aesthetics, convenience of taking drugs, economy, etc

as mentioned above, pharmaceutical packaging materials and forms will give full play to their unique advantages in the highly competitive market, and will find the best "selling points" in the market competition

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